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Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells

✍ Scribed by Dharminder Chauhan; Madhavi Bandi; Ajita V. Singh; Arghya Ray; Noopur Raje; Paul Richardson; Kenneth C. Anderson


Book ID
108677459
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
728 KB
Volume
155
Category
Article
ISSN
0007-1048

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## Abstract 1q rearrangement is a remarkably frequent secondary chromosomal change in both non‐Hodgkin's lymphoma (NHL) and multiple myeloma (MM), where it is associated with tumor progression. To gain insight into 1q rearrangement‐associated disease mechanisms, we used fluorescence in situ hybridi