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Preclinical evaluation of a monoclonal antibody targeting the epidermal growth factor receptor as a radioimmunodiagnostic and radioimmunotherapeutic agent

✍ Scribed by GL Ray; KE Baidoo; KJ Wong; M Williams; K Garmestani; MW Brechbiel; DE Milenic


Book ID
111219249
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
363 KB
Volume
157
Category
Article
ISSN
0007-1188

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A monoclonal antibody to the human epide
✍ Michael D. Waterfield; Elaine L. V. Mayes; Paul Stroobant; Paul L. P. Bennet; Su πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 844 KB

## Abstract A monoclonal antibody of the IgG class, EGFR1, has been isolated using cells of the epidermoid carcinoma line A431 as immunogen. The A431 antigen recognized by EGFR1 has an apparent molecular weight of approximately 175,000, is a cell‐surface molecule which can be specifically cross‐lin