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Preclinical efficacy of growth hormone-releasing hormone antagonists for androgen-dependent and castration-resistant human prostate cancer

✍ Scribed by Fahrenholtz, C. D.; Rick, F. G.; Garcia, M. I.; Zarandi, M.; Cai, R.-Z.; Block, N. L.; Schally, A. V.; Burnstein, K. L.

Book ID: 124089799
Publisher: National Academy of Sciences
Year: 2014
Tongue: English
Weight: 862 KB
Volume: 111
Category: Article
ISSN: 0027-8424
DOI: 10.1073/pnas.1323102111

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## Background: Hormones like bombesin (bn)/gastrin-releasing peptide (grp) and luteinizing hormone-releasing hormone (lh-rh) and growth factors such as epidermal growth factor (egf) might be involved in the relapse of prostate cancer under androgen ablation therapy. interference with receptors for