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Preclinical antitumor activity of orally administered platinum (IV) complexes

✍ Scribed by William C. Rose; Alfred R. Crosswell; John E. Schurig; Anna Maria Casazza


Publisher
Springer
Year
1993
Tongue
English
Weight
816 KB
Volume
32
Category
Article
ISSN
0344-5704

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Antitumor activity of platinum complexes
✍ Jaroslav DrobnΓ­k πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 638 KB

Contemporary ideas about the mechanism of antitumor activity of platinum complexes are reviewed and discussed. The induction of SOS functions in bacteria is emphasized and an analogous mechanism in animal cells is suggested. The fate of the leaving ligand in the body is not known. Therefore the comp