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Preclinical and clinical studies on immunogenicity and safety of the HIV-1 p17-based synthetic peptide AIDS vaccine — HGP-30-KLH

✍ Scribed by Paul H. Naylor; Marcelo B. Sztein; Saiji Wada; Scott Maurer; Daniel Holterman; Janet E. Kirkley; Cartha W. Naulor; Bernard C. Zook; Richard A. Hitzelberg; Clarence J. Gibbs Jr; Daniel Zagury; Ammar Achour; Carol O'Toole; Brian Gazzard; Mike Youle; Adan Rios; Prem S. Sarin; Allan L. Goldstein

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 864 KB
Volume: 13
Category: Article
ISSN: 0192-0561
DOI: 10.1016/0192-0561(91)90133-r

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## Abstract Several studies have suggested that HIV‐1 p17 matrix protein may play an important role in AIDS pathogenesis, since anti‐p17 antibodies represent a serological marker of disease progression during HIV‐1 infection both in adults and children. Moreover, it has been recently reported that