✦ LIBER ✦

Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma

✍ Scribed by Xiaojing Wang; Anthony L. Sinn; Karen Pollok; George Sandusky; Shuhong Zhang; Li Chen; Jing Liang; Colin D. Crean; Attaya Suvannasankha; Rafat Abonour; Carolyn Sidor; Mark R. Bray; Sherif S. Farag

Book ID: 108676839
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 946 KB
Volume: 150
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2010.08248.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Preclinical activity of P276-00, a novel

Preclinical activity of P276-00, a novel small-molecule cyclin-dependent kinase inhibitor in the therapy of multiple myeloma

✍ Raje, N; Hideshima, T; Mukherjee, S; Raab, M; Vallet, S; Chhetri, S; Cirstea, D; 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 354 KB

Antitumour activity of oral E7080, a nov

Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts

✍ Skjalg Bruheim; Alexandr Kristian; Toshimitsu Uenaka; Zhenhe Suo; Akihiko Tsuruo 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 588 KB

## Abstract E7080 is an inhibitor of multiple tyrosine kinases, several of which have pro‐angiogenic properties, including receptors for VEGF, FGF, SCF and PDGF. We undertook our study to evaluate the preclinical activity of E7080 in human sarcomas. The antitumour activity of orally administered E7

Activity of a novel Aurora kinase inhibi

Activity of a novel Aurora kinase inhibitor against the T315I mutant form of BCR-ABL: In vitro and in vivo studies

✍ Daigo Akahane; Tetsuzo Tauchi; Seiichi Okabe; Kousuke Nunoda; Kazuma Ohyashiki 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 451 KB

Phase I, pharmacokinetic, and biological

Phase I, pharmacokinetic, and biological studies of TSU-68, a novel multiple receptor tyrosine kinase inhibitor, administered after meals with solid tumors

✍ Haruyasu Murakami; Yutaka Ueda; Tatsu Shimoyama; Noboru Yamamoto; Yasuhide Yamad 📂 Article 📅 2010 🏛 Springer 🌐 English ⚖ 278 KB

AT7519, A novel small molecule multi-cyc

AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition

✍ Santo, L; Vallet, S; Hideshima, T; Cirstea, D; Ikeda, H; Pozzi, S; Patel, K; Oka 📂 Article 📅 2010 🏛 Nature Publishing Group 🌐 English ⚖ 938 KB

Phase I and pharmacokinetic study of TSU

Phase I and pharmacokinetic study of TSU-68, a novel multiple receptor tyrosine kinase inhibitor, by twice daily oral administration between meals in patients with advanced solid tumors

✍ Yutaka Ueda; Tatsu Shimoyama; Haruyasu Murakami; Noboru Yamamoto; Yasuhide Yamad 📂 Article 📅 2010 🏛 Springer 🌐 English ⚖ 472 KB