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Precise mapping of the fragile site FRA12A on chromosome 12q13.1

✍ Scribed by Birgitta Winnepenninckx; Edwin Reyniers; Paul Bossuyt; Arie Smits; Jan Wauters; R. Frank Kooy


Book ID
114432572
Publisher
John Wiley and Sons
Year
2001
Weight
393 KB
Volume
1
Category
Article
ISSN
1466-920X

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## Abstract Common fragile sites (CFSs) are expressed as chromosome gaps in cells of different species including human and mouse as a result of the inhibition of DNA replication. They may serve as hot spots for DNA breakage in processes such as tumorigenesis and chromosome evolution. Using multicol