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Precise Characterization of Human Histones in the H2A Gene Family by Top Down Mass Spectrometry

โœ Scribed by Boyne, Michael T.; Pesavento, James J.; Mizzen, Craig A.; Kelleher, Neil L.


Book ID
126993142
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
336 KB
Volume
5
Category
Article
ISSN
1535-3893

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The human histone H2A.X gene is unusual in that its transcripts are alternatively processed to yield two species, one a 0.6-kb replication-linked histone mRNA and the other a 1.6-kb polyadenylated mRNA. The H2A.X gene has been localized by fluorescence in situ hybridization to chromosome 11q23.2-q23