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Preapoptotic chromatin changes induced by ultraviolet B irradiation in human erythroleukemia K562 cells

โœ Scribed by Kinga Ujvarosi; Janos Hunyadi; Gabor Nagy; Imre Pocsi; Gaspar Banfalvi


Publisher
Springer
Year
2007
Tongue
English
Weight
557 KB
Volume
12
Category
Article
ISSN
1360-8185

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Ultraviolet (UV) light is a strong apoptotic trigger that can induce a caspase-dependent biochemical change in cells. We previously showed that UV irradiation can elicit caspase-3 activation and the subsequent cleavage and activation of p21-activated kinase 2 (PAK2) in human epidermal carcinoma A431