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Preadipocyte differentiation blocked by prostaglandin stimulation of prostanoid FP2 receptor in murine 3T3-L1 cells

โœ Scribed by David A. Casimir; Carolyn Wilson Miller; James M. Ntambi


Book ID
114428565
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
556 KB
Volume
60
Category
Article
ISSN
0301-4681

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## Abstract Prostaglandin F2ฮฑ (PGF2ฮฑ) is a potent paracrine inhibitor of adipocyte differentiation. Here we show that treatment of differentiating 3T3โ€L1 preadipocytes with PGF2ฮฑ induces the expression of DEC1, a transcriptional repressor that has previously been implicated in the inhibition of adi