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Pre-transplant elevations of interleukin-12 and interleukin-10 are associated with acute rejection after renal transplantation

✍ Scribed by Jason T Fitzgerald; Jeremy R Johnson; Richard V Perez

Book ID: 110889388
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 96 KB
Volume: 18
Category: Article
ISSN: 0902-0063
DOI: 10.1111/j.1399-0012.2004.00185.x

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## Abstract Cytokines such as tumour necrosis factor alpha (TNF‐α) and interleukin 6 (IL‐6) are thought to be important in the pathogenesis of post‐transplant cytomegalovirus (CMV) disease. CMV infection increases the production of TNF‐α and IL‐6. Conversely, TNF‐α switches on the replication of CM