Pre-S Deletion and Complex Mutations of Hepatitis B Virus Related to Advanced Liver Disease in HBeAg-Negative Patients
✍ Scribed by Chien–Hung Chen; Chao–Hung Hung; Chuan–Mo Lee; Tsung–Hui Hu; Jing–Houng Wang; Jyh–Chwan Wang; Sheng–Nan Lu; Chi–Sin Changchien
- Book ID
- 119760056
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 355 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0016-5085
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## Abstract Studies on the characteristics of mutations within the hepatitis B virus (HBV) genome, their roles in the pathogenesis of advanced liver diseases, and the involvement of host properties of HBV‐infected individuals have not been conducted in subgenotype B3‐infected populations. For addre
The peptide which is encoded by the pre-S(2) region of hepatitis B virus DNA, the pre-S(2) antigen, was determined quantitatively by an enzyme immunoassay system employing monoclonal antibodies. The prevalence and titer of pre-S(2)Ag were 91.9% (91/99) and 10,356 2 19,053 units (mean f S.D., arbitra