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Pre-polarized saline: an in vivo feasibility study of a potential contrast agent

✍ Scribed by Ian R. Young; Nandita M. deSouza; Alasdair S. Hall; Andreanna D. Williams; Joseph V. Hajnal; Glyn A. Coutts

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
199 KB
Volume
12
Category
Article
ISSN
0952-3480

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✦ Synopsis

The potential for using pre-polarized liquids as contrast agents in vivo is investigated and the feasibility of the method demonstrated. In this study we show the enhancement obtained following intravenous delivery of prepolarized saline into the antecubital vein of a volunteer. This form of contrast agent provides signal gain on time scales commensurate with its T 1 and allows repeated doses to be administered, thus making alternate acquisitions of data with and without enhancement practicable.

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