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Pre-erythrocytic-stage immune effector mechanisms in Plasmodium spp. infections

✍ Scribed by Doolan, D. L.; Hoffman, S. L.


Book ID
120153286
Publisher
The Royal Society
Year
1997
Tongue
English
Weight
301 KB
Volume
352
Category
Article
ISSN
0080-4622

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Duffy antigen is the receptor used by Plasmodium vivax to invade erythrocytes. Consequently, individuals lacking Duffy antigen [Fy(-)] do not develop blood-stage infections. We hypothesized that naturally exposed Fy(-) humans may develop immune responses mainly to pre-erythrocytic stages and could b