𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pre-clinical development of farnesyltransferase inhibitors

✍ Scribed by Robert B. Lobell; Nancy E. Kohl


Book ID
110231340
Publisher
Springer
Year
1998
Tongue
English
Weight
603 KB
Volume
17
Category
Article
ISSN
0167-7659

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Advances in the development of farnesylt
✍ Wenli Yang; Keith Del Villar; Jun Urano; Hiroshi Mitsuzawa; Fuyuhiko Tamanoi πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 92 KB πŸ‘ 1 views

A variety of compounds that show promise in cancer chemotherapy and chemoprevention have been identified as farnesyltransferase inhibitors. These can be classified into mainly two different types of inhibitors, farnesyl diphosphate competitors and CAAX peptidomimetics. The former type acts by compet

Development of Benzophenone-Based Farnes
✍ Katja Kohring; Jochen Wiesner; Mirko AltenkΓ€mper; Jacek Sakowski; Katrin Silber; πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 572 KB

## Abstract The development of farnesyltransferase inhibitors directed against __Plasmodium falciparum__ is a strategy towards new drugs against malaria. Previously, we described benzophenone‐based farnesyltransferase inhibitors with high inβ€…vitro antimalarial activity but no inβ€…vivo activity. Thro