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Practical synthesis of Ambrox® from farnesyl acetate involving lipase catalyzed resolution

✍ Scribed by Hisahide Tanimoto; Takayuki Oritani

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 504 KB
Volume: 7
Category: Article
ISSN: 0957-4166
DOI: 10.1016/0957-4166(96)00203-0

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✦ Synopsis

EnantiomericaUy pure Ambrox ® was synthesized from (-)-13,14,15,16-tetranor-8or, 12-1abdanediol, which was prepared by lipase catalyzed kinetic resolution of (+)-drimane-8,11-diol.

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