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Practical synthesis of a new analytical construct: thiopyrimidine safety-catch linker for facile monitoring of solid-phase chemistry

✍ Scribed by Olivier Lorthioir; Stephen C. McKeown; Nigel J. Parr; Melanie Washington; Stephen P. Watson

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
107 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

We report here a new analytical construct based on a thiopyrimidine safety-catch linker. This construct adds to the existing portfolio of linkers available for facile monitoring of reactions conducted on solid support. A practical solution phase synthesis of the precursor is described, together with the proof of concept and cleavage protocols.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Practical Synthesis
ChemInform Abstract: Practical Synthesis of a New Analytical Construct: Thiopyrimidine Safety-Catch Linker for Facile Monitoring of Solid-Phase Chemistry.
✍ Olivier Lorthioir; Stephen C. McKeown; Nigel J. Parr; Melanie Washington; Stephe πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 2 views

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The use of a dithiane protected benzoin
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