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Practical Synthesis of a Highly Functionalized Thiazole Ketone.

✍ Scribed by Lisa F. Frey; Karen M. Marcantonio; Chen-yi Chen; Debra J. Wallace; Jerry A. Murry; Lushi Tan; Weirong Chen; Ulf H. Dolling; Edward J. J. Grabowski

Publisher
John Wiley and Sons
Year
2003
Weight
212 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract A series of di‐ and trisubstituted cyclopropyl ketones **11** were prepared by irradiation of ketones **3** and **5**, which bear a leaving group adjacent to the carbonyl C‐atom. The required ketones **3** could be easily synthesized either by functionalization of ketones **1** with a h