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Practical Syntheses of (2S)-R207910 and (2R)-R207910 (Eur. J. Org. Chem. 11/2011)

✍ Scribed by Srivari Chandrasekhar; G. S. Kiran Babu; Debendra K. Mohapatra

Book ID: 102830161
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 952 KB
Volume: 2011
Category: Article
ISSN: 1434-193X
DOI: 10.1002/ejoc.201190024

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✦ Synopsis

Abstract

The cover picture shows the syntheses (on a gram scale) of (2__S__)‐R207910 and (2__R__)‐R207910, which can be utilized to stop the spread of tuberculosis. The key steps involved in the syntheses include Sharpless asymmetric epoxidation, regioselective epoxide ring opening and modified allylzinc bromide addition. Details are discussed in the article by S. Chandrasekhar, G. S. K. Babu, and D. K. Mohapatra on p. 2057 ff.

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