Practical Flow Cytometry in Haematology Diagnosis Dr Mike Leach, Dr Mark Drummond and Dr Allyson Doig Department of Haematology, Gartnavel General Hospital, Glasgow, UK Haematology Department, Beatson West of Scotland Cancer Centre, Glasgow, UK Department of Haematology, Gartnavel Hospital, Glasgow, UK The accurate diagnosis of haematologic malignancies is a complex and challenging task. It routinely involves morphologic, molecular, cytogenetic and flow cytometric expertise. To determine what treatment protocol will be followed, it is vital to integrate, interpret and report these results accurately. Flow cytometry is key in this diagnostic pathway. This book guides the reader as to how flow cytometry results should be interpreted and applied to optimize patient care. At the core of this text is an appreciation of clinical, morphological and immunophenotypic correlation and the importance of constant liaison and discussion between the medical and scientific teams. The authors present a logical and practical approach to the diagnosis of blood disorders (both neoplastic and reactive) and evaluate the diagnostic applications of flow cytometry. Practical Flow Cytometry in Haematology Diagnosis provides: A clinical reference source on all aspects of flow cytometry, covering both malignant and benign conditions Carefully chosen real-life cases in each chapter, complemented by high quality morphological images Help in making a diagnosis, together with an understanding of the limitations of the technique and the potential pitfalls All those who instigate, perform, interpret or act upon flow cytometry patient material will find this book an invaluable guide. Titles of related interest Ortolani: Flow Cytometry of Hematological Malignancies (2011) ISBN: 978-1-4443-3588-0 Kottke-Marchant: Laboratory Hematology Practice (2012) ISBN: 978-1-4051-6218-0Content:
Chapter 1 Introduction (pages 1โ2):
Chapter 2 Principles of Flow Cytometry (pages 3โ19):
Chapter 3 Limitations (pages 20โ30):
Chapter 4 Normal Blood and Bone Marrow Populations (pages 31โ42):
Chapter 5 Acute Leukaemia (pages 43โ99):
Chapter 6 Chronic Lymphoid Leukaemias and Exfoliating Lymphoma (pages 100โ151):
Chapter 7 Myelodysplastic Syndromes and Myeloproliferative Neoplasms (pages 152โ172):
Chapter 8 Disorders of Plasma Cells (pages 173โ183):
Chapter 9 Minimal Residual Disease (pages 184โ201):
Chapter 10 Red Cells, Leucocytes and Platelets (pages 202โ224):
Chapter 11 Reactive and Non?neoplastic Phenomena (pages 225โ242):