𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies

✍ Scribed by L. Aarons; M. Rowland; L. P. Balant; F. Mentré; P. L. Morselli; J. -L. Steimer; S. Vozeh


Book ID
104672124
Publisher
Springer
Year
1996
Tongue
English
Weight
484 KB
Volume
49
Category
Article
ISSN
0031-6970

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Practical issues in distributed paramete
✍ N. Point; A. Vande Wouwer; M. Remy 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 756 KB

Parameter estimation in nonlinear distributed-parameter systems is usually accomplished by minimizing an output least-square criterion, which is defined implicitly through the solution of the model equations. This paper addresses itself to two important practical issues of the parameter-estimation p