๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Practical aspects of the use of high performance liquid chromatography combined with simultaneous nuclear magnetic resonance and mass spectrometry

โœ Scribed by S. D. Taylor; B. Wright; E. Clayton; I. D. Wilson

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
69 KB
Volume
12
Category
Article
ISSN
0951-4198

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โœฆ Synopsis

Applications of liquid Chromatography/nuclear magnetic resonance/mass spectrometry have recently been described which have shown the benefits of this double hyphenation for identification and structure determination. However, the combination of HPLC/NMR and HPLC/MS is not without its difficulties and, as the number of applications of this technology has increased in our laboratory, we have gained considerable insight into the pitfalls that can be encountered when attempting to perform HPLC/NMR/MS. Guidelines are presented to facilitate the effective combination of HPLC with NMR and MS in tandem together with some suggestions as to how the technique may develop.

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