Practicable synthesis of (1R,4R)-5-(ℓ-menthoxy)-2-azabicyclo[2.2.0]-hex-5-en-3-one and its derivatives: New building blocks for carbapenem nuclei
✍ Scribed by Masayuki Sato; Nobuya Katagiri; Makoto Muto; Toru Haneda; Chikara Kaneko
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 234 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Enantioselective synthesis of (lR,4R)-2-azabicyclo[2.2.01hexane-3,5-dione and (lR,4R,SS)-5-hydroxy-2-azabicyclo[2.2.0lhexan-3-one (new building blocks for carbapenems) from 4-(&menthoxy)-
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The isolation and determination of the structure of thienamycin together with the discovery of the monobactam antibiotics gave renewed impetus to the synthesis of plactams.