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PPARγ-dependent and -independent effects of Rosiglitazone on lipotoxic human pancreatic islets

✍ Scribed by Brigitte Vandewalle; Ericka Moerman; Bruno Lefebvre; Frédérique Defrance; Valéry Gmyr; Bruno Lukowiak; Julie Kerr Conte; François Pattou


Book ID
116296166
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
145 KB
Volume
366
Category
Article
ISSN
0006-291X

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## Abstract Conjugated linoleic acid (CLA) has been shown to exert beneficial effects against carcinogenesis, atherosclerosis and diabetes. It has been demonstrated that CLA modulates lipid metabolism through the activation of peroxisome proliferator‐activated receptors (PPARs). The PPAR family com