𝔖 Bobbio Scriptorium
✦   LIBER   ✦

PPARγ and colorectal carcinoma: Conflicts in a nuclear family

✍ Scribed by Seed, Brian

Book ID
109628406
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
59 KB
Volume
4
Category
Article
ISSN
1078-8956

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

PPARγ inhibitors reduce tubulin protein
PPARγ inhibitors reduce tubulin protein levels by a PPARγ, PPARδ and proteasome-independent mechanism, resulting in cell cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells
✍ Katherine L. Schaefer; Hirokazu Takahashi; Victor M. Morales; Gianni Harris; Sus 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 827 KB

## Abstract The nuclear transcription factor peroxisome proliferator‐activated receptor‐gamma (PPARγ) has been identified as an important therapeutic target in murine models of colorectal cancer (CRC). To examine whether PPARγ inhibition has therapeutic effects in late‐stage CRC, the effects of PPA

Expression of heavy subunit of γ-glutamy
Expression of heavy subunit of γ-glutamylcysteine synthetase (γ-GCSh) in human colorectal carcinoma
✍ Shigeru Tatebe; Hitoshi Unate; Frank A. Sinicrope; Takashi Sakatani; Kenji Sugam 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 872 KB

## Abstract Gamma‐glutamylcysteine synthetase (γ‐GCS) is a heterodimer consisting of heavy (γ‐GCSh) and light (γ‐GCSl) subunits. γ‐GCS catalyzes the rate‐limiting __de novo__ biosynthesis of glutathione (GSH), an abundant physiological antioxidant that plays important roles for regulating oxidative