pp60c-src Is a Negative Regulator of Laminin-1-Mediated Neurite Outgrowth in Chick Sensory Neurons

NRAGE is a negative regulator of nerve g

NRAGE is a negative regulator of nerve growth factor-stimulated neurite outgrowth in PC12 cells mediated through TrkA-ERK signaling

✍ Zhenhua Feng; Kaizhen Li; Mei Liu; Chuanjun Wen 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 338 KB 👁 1 views

## Abstract NRAGE, also denominated as MAGE‐D1 or Dlxin‐1, is firstly identified as a molecule interacting with NGF low affinity receptor p75NTR. It facilitates cell cycle arrest and NGF‐dependent neuronal apoptosis. Here we report that NRAGE is downregulated while p75NTR is upregulated during the