## Abstract The identification and characterization of genes that influence the risk of common, complex multifactorial diseases, primarily through interactions with other genes and other environmental factors, remains a statistical and computational challenge in genetic epidemiology. This challenge
✦ LIBER ✦
Powerful Tests for Detecting a Gene Effect in the Presence of Possible Gene–Gene Interactions Using Garrote Kernel Machines
✍ Scribed by Arnab Maity; Xihong Lin
- Book ID
- 109224530
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 275 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0006-341X
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## Abstract Despite tremendous efforts, few genes involved in the susceptibility for complex disorders have been identified. One explanation is that these disorders are a result of an interaction between genes and environment, and under such conditions, it may be difficult to measure the true genet