Examining the effect of linkage disequil
โ
Yoonhee Kim; Priya Duggal; Elizabeth M. Gillanders; Ho Kim; Joan E. Bailey-Wilso
๐
Article
๐
2008
๐
John Wiley and Sons
๐
English
โ 396 KB
## Abstract Because most multipoint linkage analysis programs currently assume linkage equilibrium between markers when inferring parental haplotypes, ignoring linkage disequilibrium (LD) may inflate the Type I error rate. We investigated the effect of LD on the Type I error rate and power of nonpa