Power for Genetic Association Studies with Random Allele Frequencies and Genotype Distributions
✍ Scribed by Walter T. Ambrosius; Ethan M. Lange; Carl D. Langefeld
- Book ID
- 119770025
- Publisher
- American Society of Human Genetics
- Year
- 2004
- Tongue
- English
- Weight
- 302 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/383282
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract With the emergence of Biobanks alongside large‐scale genome‐wide association studies (GWAS) we will soon be in the enviable situation of obtaining precise estimates of population allele frequencies for SNPs which make up the panels in standard genotyping arrays, such as those produced f
## Abstract Genetic association studies are becoming commonplace due to the availability of cost‐effective yet sophisticated DNA sequencing and genotyping resources and technologies. In addition, technologies designed to identify molecular and subclinical phenotypes that reflect disease pathogenesi
## Abstract Family‐based association tests (FBATs) provide simple and powerful tests to detect association between a genetic marker and a disease‐susceptibility locus, manifest in subjects by a phenotype or disease trait. Here we propose a new class of conditional tests for family‐based association