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Power Calculations for a General Class of Tests of Linkage and Association That Use Nuclear Families with Affected and Unaffected Sibs

✍ Scribed by Norman L. Kaplan; Eden R. Martin


Book ID
115648664
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
146 KB
Volume
60
Category
Article
ISSN
0040-5809

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On a general class of conditional tests
✍ Christoph Lange; Nan M. Laird 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 208 KB 👁 2 views

## Abstract Family‐based association tests (FBATs) provide simple and powerful tests to detect association between a genetic marker and a disease‐susceptibility locus, manifest in subjects by a phenotype or disease trait. Here we propose a new class of conditional tests for family‐based association