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Power and Sample Size Calculation of Comparative Diagnostic Accuracy Studies with Multiple Correlated Test Results

✍ Scribed by Aiyi Liu; Enrique F. Schisterman; Madhu Mazumdar; Jiang Hu


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
163 KB
Volume
47
Category
Article
ISSN
0323-3847

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✦ Synopsis


We consider the power and sample size calculation of diagnostic studies with normally distributed multiple correlated test results. We derive test statistics and obtain power and sample size formulas. The methods are illustrated using an example of comparison of CT and PET scanner for detecting extra-hepatic disease for colorectal cancer.