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Powder X-ray diffraction method for the quantification of cocrystals in the crystallization mixture

✍ Scribed by Padrela, Luis; de Azevedo, Edmundo Gomes; Velaga, Sitaram P.

Book ID
111942952
Publisher
Informa plc
Year
2011
Tongue
English
Weight
850 KB
Volume
38
Category
Article
ISSN
0363-9045

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A method of analyzing mixtures of APIs and excipients using X-ray powder diffraction is described. It uses a simple algorithm based on linear regression in which the pure component phases are fitted to the mixture pattern using linear least squares. Unlike many methods that use only the peaks in the