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Potentiometric titrations and oxidation-reduction potentials of manganese and copper-zinc superoxide dismutases

โœ Scribed by Lawrence, Glen D.; Sawyer, Donald T.

Book ID
121856095
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
754 KB
Volume
18
Category
Article
ISSN
0006-2960

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Copper/zinc (Cu/ZnSOD) and manganese (MnSOD) superoxide dismutases which catalyze the dismutation of toxic superoxide anion, O(2-)-, to O2 and H2O2, play a major role in protecting cells from toxicity of oxidative stress. However, cells overexpressing either form of the enzyme show signs of toxicity