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Potentiation of thioacetamide-induced hepatotoxicity in alloxan- and streptozotocin-diabetic rats

โœ Scribed by El-Hawari, A.Monaem; Plaa, Gabriel L.


Book ID
124124814
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
522 KB
Volume
17
Category
Article
ISSN
0378-4274

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Pharmacokinetics and pharmacodynamics of
โœ Yu C. Kim; Eun Y. Oh; So H. Kim; Myung G. Lee ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 107 KB ๐Ÿ‘ 2 views

The pharmacokinetic and pharmacodynamic parameters of torasemide were compared after intravenous administration at a dose of 2 mg/kg to diabetic rats induced by alloxan (DMIA) or streptozotocin (DMIS), and their respective control rats. It was reported that torasemide was mainly metabolized via CYP2