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Potentiation of the mutagenicity and recombinagenicity of bleomycin in yeast by unconventional intercalating agents

✍ Scribed by George R. Hoffmann; Amanda M. Laterza; Katelyn E. Sylvia; Jason P. Tartaglione


Book ID
102187931
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
257 KB
Volume
52
Category
Article
ISSN
0893-6692

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Modulation of bleomycin-induced mitotic
✍ Hoffmann, George R. ;Quaranta, Joseph L. ;Shorter, Rose A. ;Littlefield, L. Gayl πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 991 KB

The cancer chemotherapy drug bleomycin (BLM) is a potent inducer of genetic damage in a wide variety of assays. The radioprotectors cysteamine (CSM) and WR-1065 have been shown in previous studies to potentiate the induction of micronuclei and chromosome aberrations by BLM in Go human lymphocytes. B