Potentiation of the Growth-Inhibitory Effects of Vitamin D in Prostate Cancer by Genistein
β Scribed by Aruna V. Krishnan; Srilatha Swami; Jacqueline Moreno; Rumi B. Bhattacharyya; Donna M. Peehl; David Feldman
- Book ID
- 109381302
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 38 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0029-6643
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## Abstract Prostate cancer (PCa) cells express vitamin D receptors (VDR) and 1,25βdihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) inhibits the growth of epithelial cells derived from normal, benign prostate hyperplasia, and PCa as well as established PCa cell lines. The growth inhibitory effects of 1,25(O
## Background: There is strong epidemiological evidence that prostate disease is significantly less prevalent in the orient, where the intake of soy products is very high, than in the united states. we therefore undertook a study of the effects of genistein, a major component of soy, on growth of h