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Potentiation of the antitumor effect of calcium phosphate cement containing anticancer drug and caffeine on rat osteosarcoma

✍ Scribed by Yoshikazu Tanzawa; Hiroyuki Tsuchiya; Toshiharu Shirai; Hideji Nishida; Katsuhiro Hayashi; Akihiko Takeuchi; Masami Kawahara; Katsuro Tomita

Publisher
Springer Japan
Year
2011
Tongue
English
Weight
419 KB
Volume
16
Category
Article
ISSN
0949-2658

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✍ Julia Schnieders; Uwe Gbureck; Elke Vorndran; Michael Schossig; Thomas Kissel πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 1004 KB

## Abstract The influence of porosity on release profiles of antibiotics from calcium phosphate composites was investigated to optimize the duration of treatment. We hypothesized, that by the encapsulation of vancomycin‐HCl into biodegradable microspheres prior admixing to calcium phosphate bone ce