Potentiation of the activity of bone morphogenetic protein-2 in bone regeneration by a PLA–PEG/hydroxyapatite composite
✍ Scribed by Takashi Kaito; Akira Myoui; Kunio Takaoka; Naoto Saito; Masataka Nishikawa; Noriyuki Tamai; Hajime Ohgushi; Hideki Yoshikawa
- Book ID
- 108069331
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 333 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0142-9612
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## Abstract Bone morphogenetic proteins (BMPs) are the most potent osteoinductive growth factors. However, a delivery system is essential to take advantage of the osteoinductive effect of BMPs. In the present study, we tested the suitability of apatite‐coated poly(D,L‐lactide‐__co__‐glycolide)/nano
To determine if recombinant human bone morphogenetic protein-2 (rhBMP-2) can be adsorbed onto porous ceramic hydroxyapatite (HA) and promote the integration of HA to host bone, 54 subperiosteal pockets were created on the skulls of 19 adult Pasteurella-free white rabbits. Fourteen HA implants were s