Potentiation of Photodynamic Therapy with Hypericin by Mitomycin C in the Radiation-induced Fibrosarcoma–1 Mouse Tumor Model

Efficacy of antitumoral photodynamic the

Efficacy of antitumoral photodynamic therapy with hypericin: Relationship between biodistribution and photodynamic effects in the RIF-1 mouse tumor model

✍ Bin Chen; Yan Xu; Tania Roskams; Els Delaey; Patrizia Agostinis; Jackie R. Vande 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 654 KB

We investigated the hypericin-mediated PDT effects on the tumor and normal skin and in correlation with its biodistribution. These studies were carried out on C3H mice bearing RIF-1 tumors. The hypericin distribution and PDT effects were recorded at different intervals (0.5-24 hr) after intravenous