Modulation of cis-diamminedichloroplatin
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Stephen C. Mann; Paul A. Andrews; Stephen B. Howell
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Article
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1991
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John Wiley and Sons
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French
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We have determined the effect of forskolin, an adenyl cy-Clare agonist, and 3-isobutyl-I-methylxanthine (IBMX), a phosphodiesterase inhibitor, on the accumulation and cytotoxicity of cisplatin (DDP) in 2008 human ovarian carcinoma cells. In DDP-sensitive 2008 cells, forskolin and IBMX caused 2. I -f