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Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells

✍ Scribed by Bo Hellman


Book ID
118947413
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
594 KB
Volume
23
Category
Article
ISSN
1532-8600

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Effects of the hypoglycaemic drugs repag
✍ J. Gromada; S. Dissing; H. Kofod; J. FrØkjΓ†r-Jensen πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 807 KB

The present study demonstrates the action of the hypoglycaemic drugs repaglinide and glibenclamide in cultured newborn rat islet cells and mouse flTC3 cells. In cell-attached membrane patches of newborn rat islet cells repaglinide (10 nmol/ 1) and glibenclamide (20 nmol/1) decrease the open probabil