Potential therapeutic strategy for oral squamous cell carcinoma by ErbB3-binding protein 1 gene transfer

Suppression of salivary adenoid cystic c

Suppression of salivary adenoid cystic carcinoma growth and metastasis by ErbB3 binding protein Ebp1 gene transfer

✍ Youcheng Yu; Wantao Chen; Yuexing Zhang; Anne W. Hamburger; Hongya Pan; Zhiyuan 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 285 KB

## Abstract Ebp1, an ErbB3 binding protein and downstream effector of the ErbB signaling network was shown to be a potent tumor suppressor in breast and prostate adenocarcinomas. We hypothesized that the inhibitory properties of the __ebp1__ gene could also be beneficial if ectopically expressed in