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Potential role for human P-glycoprotein in the transport of lacosamide

✍ Scribed by Zhang, Chunbo; Chanteux, Hugues; Zuo, Zhong; Kwan, Patrick; Baum, Larry

Book ID
120193097
Publisher
Wiley (Blackwell Publishing)
Year
2013
Tongue
English
Weight
482 KB
Volume
54
Category
Article
ISSN
0013-9580

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## Abstract ## Introduction Verapamil is a calcium channel blocker that also inhibits the P‐glycoprotein (Pgp) membrane transporter. We have found that administration of verapamil with a recognised antidepressant improves clinical outcome in previously treatment resistant cases despite the fact th