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Potential radiation-sensitizing effect of semisynthetic epothilone B in human lung cancer cells

โœ Scribed by Jae-Chul Kim; Jae-Sung Kim; Debabrata Saha; Qianwen Cao; Yu Shyr; Hak Choy


Book ID
119513901
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
184 KB
Volume
68
Category
Article
ISSN
0167-8140

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Substantial controversy surrounds our understanding of the effect of p53 status on radiation sensitivity. To assess directly the role of p53 expression on radiation sensitivity, we chose a conditional expression system using a temperature-sensitive murine p53 that permitted each cell line to act as