Natural cyclopeptides as leads for novel
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Cavelier, Florine; Verducci, Jean; AndrΓ©, FranΓ§ois; Haraux, Francis; Sigalat, Cl
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Article
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1998
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John Wiley and Sons
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English
β 389 KB
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Difficulties in synthesis make natural cyclopeptides challenging targets for chemists. Our interest focused on two natural toxic cyclopeptide series produced by pathogenic fungi : tentoxin, The total syntheses of these two bioactive series were optimised, and several analogues were designed and syn