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Potential of hydroxyebastine and terfenadine alcohol to inhibit the human cytochrome P450 2J2 isoform

✍ Scribed by Yune-Jung Yoon, Kwang-Hyeon Liu

Book ID
113010411
Publisher
The Korean Society for Applied Biological Chemistry
Year
2011
Tongue
English
Weight
313 KB
Volume
54
Category
Article
ISSN
1738-2203

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Terfenadine (TF) is a highly potent histamine H1 receptor antagonist that in clinically effective doses is free of significant central nervous system side effects. Ketoconazole (KT) is a worldwide used oral antifungal agent with a broad spectrum of activity against both superficial and systemic myco