𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Potential mechanisms of disease progression and management of advanced-phase chronic myeloid leukemia

✍ Scribed by Jabbour, Elias J.; Hughes, Timothy P.; Cortés, Jorge E.; Kantarjian, Hagop M.; Hochhaus, Andreas


Book ID
121282492
Publisher
Informa plc
Year
2013
Tongue
English
Weight
841 KB
Volume
55
Category
Article
ISSN
1042-8194

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Repetitive DNA hypomethylation in the ad
✍ Jose Roman-Gomez; Antonio Jimenez-Velasco; Xabier Agirre; Juan A. Castillejo; Ge 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 165 KB

Repetitive elements are heavily methylated in normal tissues, but hypomethylated in malignant tissues, driving the global genomic hypomethylation found in cancer. This hypomethylation results in chromosomal instability, a well-characterized feature of the advanced phases of chronic myeloid leukemia

Practical management of patients with ch
✍ Francisco Cervantes; Michael Mauro 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB

## Abstract Although imatinib has been used as frontline therapy for chronic myeloid leukemia (CML) for nearly a decade, current debate is focused on the incorporation of newer tyrosine kinase inhibitors (TKIs) at diagnosis in light of recent US Food and Drug Administration approval of nilotinib an