✦ LIBER ✦

Potential folic acid antagonists. 5. Synthesis and biologic evaluation of N10-deazapteroic acid and N10-deazafolic acid and their 9,10-dehydro derivatives

✍ Scribed by Struck, Robert F.; Shealy, Y. Fulmer; Montgomery, John A.

Book ID: 127330133
Publisher: American Chemical Society
Year: 1971
Tongue: English
Weight: 730 KB
Volume: 14
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00290a006

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and Biological Evaluation of 9

Synthesis and Biological Evaluation of 9-Thia-5,10-dideazafolic Acid.

✍ Mark Wall; Stephen J. Benkovic 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 116 KB 👁 2 views

Synthesis and biological evaluation of 9

Synthesis and biological evaluation of 9-thia-5,10-dideazafolic acid

✍ Mark Wall; Stephen J. Benkovic 📂 Article 📅 2002 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 35 KB

## Abstract The folate analogue, 9‐thia‐5,10‐dideazafolic acid (**3b**), was obtained in an efficient two‐step procedure in an overall yield of 60%. The previously unknown intermediate dimethyl‐thiocarbamic acid S‐(2‐amino‐3,4‐dihydo‐4‐oxo‐pyrido[2,3‐__d__]pyrimidin‐6‐yl) ester (**5**) was prepared

Synthesis and antifolate evaluation of t

Synthesis and antifolate evaluation of the 10-propargyl derivatives of 5-deazafolic acid, 5-deazaaminopterin, and 5-methyl-5-deazaaminopterin

✍ Piper, J. R.; Malik, N. D.; Rhee, M. S.; Galivan, J.; Sirotnak, F. M. 📂 Article 📅 1992 🏛 American Chemical Society 🌐 English ⚖ 897 KB

Synthesis and biological evaluation of 5

Synthesis and biological evaluation of 5-deazaisofolic acid, 5-deaza-5,6,7,8-tetrahydroisofolic acid, and their N9-substituted analogues

✍ Singh, Shyam K.; Dev, Inderjit K.; Duch, David S.; Ferone, Robert; Smith, Gary K 📂 Article 📅 1991 🏛 American Chemical Society 🌐 English ⚖ 685 KB

Folate analogs. 30. Synthesis and biolog

Folate analogs. 30. Synthesis and biological evaluation of N10-propargyl-5,8-dideaza-5,6,7,8-tetrahydrofolic acid and related compounds.

✍ Nair, M. G.; Dhawan, Rashmi; Ghazala, M.; Kalman, T. I.; Gaumont, Y.; Kisliuk, R 📂 Article 📅 1987 🏛 American Chemical Society 🌐 English ⚖ 878 KB

Folate analogs. 32. Synthesis and biolog

Folate analogs. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds

✍ Patil, Sharadbala D.; Jones, Cecil; Nair, M. G.; Galivan, J.; Maley, F.; Kisliuk 📂 Article 📅 1989 🏛 American Chemical Society 🌐 English ⚖ 862 KB