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Potential Dopamine D1 Receptor Signaling Through Gaq: Behavioral and Biochemical Assessment

โœ Scribed by Aliya Frederick; Tommy Saborido; Anthony Baucum; Roger Colbran; Gregg Stanwood


Book ID
113825845
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
57 KB
Volume
33
Category
Article
ISSN
0892-0362

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Rhes and AGS1/Dexras1 affect signaling b
โœ Laura M. Harrison; YouE He ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 721 KB

The GTP binding proteins Rhes and AGS1/Dexras1 define a subfamily of the Ras superfamily and have been shown to affect signaling by G-protein-coupled receptors. We tested the effects of both proteins at an early stage of signaling by dopamine receptors, activation of adenylyl cyclase. Rhes decreased