Drug delivery of siRNA therapeutics: pot
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Daniela Reischl; Andreas Zimmer
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Article
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2009
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Elsevier Science
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English
β 539 KB
Gene therapy is a promising tool for the treatment of human diseases that cannot be cured by rational therapies. The major limitation for the use of small interfering RNA (siRNA), both in vitro and in vivo, is the inability of naked siRNA to passively diffuse through cellular membranes due to the st